Chemical Class: Valproic Acid (class)

Depakote may increase the risk of suicidal thoughts and behaviors. Risk of suicide may be exacerbated in patients who take Depakote for conditions such as bipolar disorder which already carries a higher-than-normal risk of suicide. In 2008, the FDA analyzed nearly 200 trials of epileptic drugs including Depakote.

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Plaintiff Amber G. of Oklahoma filed the Depkote birth defects lawsuit against drug makers Abbott Laboratories and Abbvie Inc. on behalf of herself and her minor child. Pregnancy Registry: If you become pregnant while taking DEPAKOTE, talk to your healthcare provider about registering with the North American Antiepileptic Drug Pregnancy Registry. You can enroll in this registry by calling toll-free 1-888-233-2334 or by visiting the website, www.aedpregnancyregistry.org. Pregnancy Registry: If you become pregnant while taking DEPAKOTE, talk to your healthcare provider about registering with the North American Antiepileptic Drug Pregnancy Registry. You can enroll in this registry by calling toll-free 1-888-233-2334 or by visiting the website, www.aedpregnancyregistry.org.

This medication is used to treat seizure disorders, migraine headaches, and the manic episodes associated with bipolar disorder. Depakote, (valproate), is an FDA-approved anti-seizure (antiepileptic) medication.

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Depakote: If daily dose >250 mg, give as divided dose. Migraine Prophylaxis. Indicated for prophylaxis of migraine headaches; there is no evidence of use for acute treatment. Depakote initial dose: 250 mg PO BID for 1 week. Depakote ER initial dose: 500 mg PO qDay for 1 week. May increase dose up to 1000 mg/day if needed. Dosage Modifications

All FDA Patients maintained on valproic acid doses of 750 mg to 4250 mg daily (given in divided doses every 6 hours) as oral Depakote (divalproex sodium) alone (n = 24) or with another stabilized antiepileptic drug [carbamazepine (n = 15), phenytoin (n = 11), or phenobarbital (n = 1)], showed comparable plasma levels for valproic acid when switching from oral Depakote to IV valproate (1-hour infusion). A federal judge has cleared the way for an investor class action lawsuit to move forward against Abbott Laboratories over its marketing of Depakote, an epilepsy drug that has been promoted off-label a Depakote use during pregnancy has also been linked to fetal valproate syndrome, a condition that can cause children to develop facial deformities that may evolve over time. Although the drug has helped millions of people, serious, life-threatening Depakote side effects have recently been exposed. Start studying Valproic acid (Depakene, Depakote). Learn vocabulary, terms, and more with flashcards, games, and other study tools. Antiepileptic drugs (AEDs), including Depakote, increase the risk of suicidal thoughts or behavior in patients taking these drugs for any indication. Tell your doctor if you have new or worsening depression, suicidal thoughts or behavior, and/or any unusual changes in mood or behavior.

Chemical Class: Valproic Acid (class) Uses for Depakote Depakote has been prescribed since 1983 1 Depakote is one of the first generation of a class of medications called antiepileptic drugs (AEDs). Depakote is used to treat complex partial seizures, simple and complex absence seizures, as well as acute manic symptoms in patients with bipolar disorder. 1-3 Generic Name: Divalproex (dye-VAL-pro-ex) Drug Class: Anticonvulsant Table of Contents Overview How to Take It Side Effects Warnings & Precautions Drug Interactions Dosage & Missing Depakote: Depakote is an antiepileptic drug (AED) used to treat seizure disorders, migraine headaches, and the manic phase of bipolar disorders. It is thought Depakote Oral: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing - WebMD. Find patient medical information for Depakote oral on WebMD including its uses, side effects and safety Valproate (marketed as Depakote, Depakote ER, Depakene, Depacon) Zonisamide (marketed as Zonegran) Although the 11 drugs listed above were the ones included in the analysis, FDA expects that the increased risk of suicidality is shared by all antiepileptic drugs and anticipates that the class labeling changes will be applied broadly. Mood, pain, seizure: Depakte is an anticonvulsant medication so can be used for seizures.
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It is not known if Depakote is safe and effective in children younger than 10 years of age. DEPAKOTE Interactions: Monitor levels of valproate, ethosuximide, other anticonvulsants, and whenever an enzyme inducer is added or withdrawn. Potentiates carbamazepine, diazepam, ethosuximide Depakote (a derivative of valproate or valproic acid) is a prescription medication used to treat seizures and manic episodes in people with bipolar disorder and to prevent migraines.
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Depakote is an anti-seizure or anti-convulsive drug used to treat epilepsy and other conditions. Abbott Laboratories is the maker and seller of Depakote, which also goes by the generic names valproic acid, valproate, and divalproex sodium.

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The medication Depakote (divalproex sodium) is an anticonvulsant. Doctors prescribe it to treat seizure disorders and to prevent migraine headaches. People also use it to manage the manic phase of bipolar disorder. Depakote side effects can be serious and sometimes fatal. Brand Name:Depakote, Depakote ER, Depakote Sprinkles Generic Name: Divalproex Sodium Drug Class:Anticonvulsants, Others In a clinical trial, the Depakote ER dose was initiated at 25 mg/kg/day and increased by 500 mg/day PO on Day 3. The dose was then adjusted to clinical response with a trough plasma concentration between 85 to 125 mcg/mL.